Functionalized Electrospun Scaffold–Human-Muscle-Derived Stem Cell Construct Promotes In Vivo Neocartilage Formation

Functionalized Electrospun Scaffold–Human-Muscle-Derived Stem Cell Construct Promotes In Vivo Neocartilage Formation

Polycaprolactone (PCL) is a non-cytotoxic, completely biodegradable biomaterial, ideal for cartilage tissue engineering. Despite drawbacks such as low hydrophilicity and lack of functional groups necessary for incorporating growth factors, it provides a proper environment for different cells, includ...

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Bibliographic Details
Main Authors: Lina Jankauskaite, Mantas Malinauskas, Lauryna Aukstikalne, Lauryna Dabasinskaite, Augustinas Rimkunas, Tomas Mickevicius, Alius Pockevičius, Edvinas Krugly, Dainius Martuzevicius, Darius Ciuzas, Odeta Baniukaitiene, Arvydas Usas
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Polymers
Subjects:
cartilage regeneration
ozone-treatment
PCL scaffold
transforming growth factor beta3
human MDSCs
scaffold–cell construct
Online Access:https://www.mdpi.com/2073-4360/14/12/2498

Internet

https://www.mdpi.com/2073-4360/14/12/2498

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