Live hot, die young: transmission distortion in recombination hotspots.
There is strong evidence that hotspots of meiotic recombination in humans are transient features of the genome. For example, hotspot locations are not shared between human and chimpanzee. Biased gene conversion in favor of alleles that locally disrupt hotspots is a possible explanation of the short...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-03-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1817654?pdf=render |