Molecular mechanisms of cadmium-induced cytotoxicity in human ovarian granulosa cells identified using integrated omics

Molecular mechanisms of cadmium-induced cytotoxicity in human ovarian granulosa cells identified using integrated omics

Epidemiological and clinical data have demonstrated that exposure to cadmium (Cd), a toxic heavy metal, is associated with an increased risk of female infertility. Granulosa cells, the main somatic cells comprising ovarian follicles, are one of the main targets of Cd in the ovaries. However, the mec...

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Bibliographic Details
Main Authors: Zili Lv, Jun Hu, Mingquan Huang, Guangrui Pan, Guofeng Xu, Meng Yang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Granulosa cells
Ovarian toxicity
Metabolomics
Transcriptomics
Multi-omics
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324001015

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http://www.sciencedirect.com/science/article/pii/S0147651324001015

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