The Phytochemical α-Mangostin Inhibits Cervical Cancer Cell Proliferation and Tumor Growth by Downregulating E6/E7-HPV Oncogenes and <i>KCNH1</i> Gene Expression

The Phytochemical α-Mangostin Inhibits Cervical Cancer Cell Proliferation and Tumor Growth by Downregulating E6/E7-HPV Oncogenes and <i>KCNH1</i> Gene Expression

Cervical cancer is the fourth most common cancer among women worldwide. The main factor associated with the onset and progression of this neoplasia is the human papillomavirus (HPV) infection. The HPV-oncogenes E6 and E7 are critical drivers of cellular transformation, promoting the expression of on...

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Bibliographic Details
Main Authors: Lorenza Díaz, Samantha V. Bernadez-Vallejo, Rafael Vargas-Castro, Euclides Avila, Karla A. Gómez-Ceja, Rocío García-Becerra, Mariana Segovia-Mendoza, Heriberto Prado-Garcia, Galia Lara-Sotelo, Javier Camacho, Fernando Larrea, Janice García-Quiroz
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
α-mangostin
cervical cancer
KCNH1
HPV
E6
E7
Online Access:https://www.mdpi.com/1422-0067/24/3/3055

Internet

https://www.mdpi.com/1422-0067/24/3/3055

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