Direct Amination of Nitroquinoline Derivatives via Nucleophilic Displacement of Aromatic Hydrogen

Direct Amination of Nitroquinoline Derivatives via Nucleophilic Displacement of Aromatic Hydrogen

The vicarious nucleophilic substitution of hydrogen (VNS) reaction in electron-deficient nitroquinolines was studied. Properties of all new products have been characterized by several techniques: MS, HRMS, FTIR, GC-MS, electronic absorption spectroscopy, and multinuclear NMR. The structures of 4-chl...

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Bibliographic Details
Main Authors: Jakub Wantulok, Daniel Swoboda, Jacek E. Nycz, Maria Książek, Joachim Kusz, Jan Grzegorz Małecki, Vladimír Kubíček
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
amination
vicarious nucleophilic substitution of hydrogen
nucleophilic aromatic substitution (S<sub>N</sub>Ar)
nitration
heterocyclic
Skraup
Online Access:https://www.mdpi.com/1420-3049/26/7/1857

Internet

https://www.mdpi.com/1420-3049/26/7/1857

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