Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against <i>Acinetobacter baumannii</i>: A Metabolomic Study

Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against <i>Acinetobacter baumannii</i>: A Metabolomic Study

Polymyxins have resurged as the last-resort antibiotics against multidrug-resistant <i>Acinetobacter baumannii</i>. As reports of polymyxin resistance in <i>A. baumannii</i> with monotherapy have become increasingly common, combination therapy is usually the only remaining tr...

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Bibliographic Details
Main Authors: Maytham Hussein, Rafah Allobawi, Irini Levou, Mark A. T. Blaskovich, Gauri G. Rao, Jian Li, Tony Velkov
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
antimicrobial resistance
antimicrobial peptides
cannabidiol
metabolomics
MDR Gram-negative
Online Access:https://www.mdpi.com/1999-4923/14/4/786

Internet

https://www.mdpi.com/1999-4923/14/4/786

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