The antifungal plant defensin HsAFP1 from Heuchera sanguinea induces apoptosis in Candida albicans

The antifungal plant defensin HsAFP1 from Heuchera sanguinea induces apoptosis in Candida albicans

Plant defensins are active against plant and human pathogenic fungi (such as Candida albicans) and baker’s yeast. However, they are nontoxic to human cells, providing a possible source for treatment of fungal infections. In this study, we characterized the mode of action of the antifungal plant defe...

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Bibliographic Details
Main Authors: An M. Aerts, Leen eBammens, Gilmer eGovaert, Didac eCarmona-Gutierrez, Frank eMadeo, Bruno P.A. Cammue, Karin eThevissen
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-03-01
Series:Frontiers in Microbiology
Subjects:
Apoptosis
Candida albicans
Mitochondria
Saccharomyces cerevisiae
mode of action
plant defensin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00047/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00047/full

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