Enhanced correlation-based linking of biosynthetic gene clusters to their metabolic products through chemical class matching

Abstract Background It is well-known that the microbiome produces a myriad of specialised metabolites with diverse functions. To better characterise their structures and identify their producers in complex samples, integrative genome and metabolome mining is becoming increasingly popular. Metabologe...

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Bibliographic Details
Main Authors: Joris J. R. Louwen, Marnix H. Medema, Justin J. J. van der Hooft
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s40168-022-01444-3