The Interplay between α-Synuclein and Microglia in α-Synucleinopathies

The Interplay between α-Synuclein and Microglia in α-Synucleinopathies

Synucleinopathies are a set of devastating neurodegenerative diseases that share a pathologic accumulation of the protein α-synuclein (α-syn). This accumulation causes neuronal death resulting in irreversible dementia, deteriorating motor symptoms, and devastating cognitive decline. While the etiolo...

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Bibliographic Details
Main Authors: Jacob S. Deyell, Manjari Sriparna, Mingyao Ying, Xiaobo Mao
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
dementia
cognition
microglia
α-synuclein
neuroinflammation
synucleinopathies
Online Access:https://www.mdpi.com/1422-0067/24/3/2477

Internet

https://www.mdpi.com/1422-0067/24/3/2477

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