Inducible expression of (pp)pGpp synthetases in Staphylococcus aureus is associated with activation of stress response genes.

Inducible expression of (pp)pGpp synthetases in Staphylococcus aureus is associated with activation of stress response genes.

The stringent response is characterized by the synthesis of the messenger molecules pppGpp, ppGpp or pGpp (here collectively designated (pp)pGpp). The phenotypic consequences resulting from (pp)pGpp accumulation vary among species and can be mediated by different underlying mechanisms. Most genome-w...

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Bibliographic Details
Main Authors: Petra Horvatek, Andrea Salzer, Andrew Magdy Fekry Hanna, Fabio Lino Gratani, Daniela Keinhörster, Natalya Korn, Marina Borisova, Christoph Mayer, Dominik Rejman, Ulrike Mäder, Christiane Wolz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009282

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https://doi.org/10.1371/journal.pgen.1009282

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