Angiogenesis in the Outer Membrane of Chronic Subdural Hematomas through Thrombin-Cleaved Osteopontin and the Integrin α9 and Integrin β1 Signaling Pathways

Angiogenesis in the Outer Membrane of Chronic Subdural Hematomas through Thrombin-Cleaved Osteopontin and the Integrin α9 and Integrin β1 Signaling Pathways

Background: A chronic subdural hematoma (CSDH) is considered to be an inflammatory and angiogenic disease. The CSDH outer membrane, which contains inflammatory cells, plays an important role in CSDH development. Osteopontin (OPN) is an extracellular matrix protein that is cleaved by thrombin, genera...

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Bibliographic Details
Main Authors: Koji Osuka, Yusuke Ohmichi, Mika Ohmichi, Satoru Honma, Chiharu Suzuki, Masahiro Aoyama, Kenichiro Iwami, Yasuo Watanabe, Shigeru Miyachi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biomedicines
Subjects:
angiogenesis
chronic subdural hematoma
integrin α9
integrin β1
N-terminal half of osteopontin
Online Access:https://www.mdpi.com/2227-9059/11/5/1440

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https://www.mdpi.com/2227-9059/11/5/1440

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