Cortical tau deposition follows patterns of entorhinal functional connectivity in aging

Cortical tau deposition follows patterns of entorhinal functional connectivity in aging

Tau pathology first appears in the transentorhinal and anterolateral entorhinal cortex (alEC) in the aging brain. The transition to Alzheimer’s disease (AD) is hypothesized to involve amyloid-β (Aβ) facilitated tau spread through neural connections. We contrasted functional connectivity (FC) of alEC...

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Bibliographic Details
Main Authors: Jenna N Adams, Anne Maass, Theresa M Harrison, Suzanne L Baker, William J Jagust
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
tau
PET
functional connectivity
aging
entorhinal cortex
Alzheimer's disease
Online Access:https://elifesciences.org/articles/49132

Internet

https://elifesciences.org/articles/49132

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