Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts

Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts

Hypoxia inducible factors (HIFs) are transcription factors that mediate the response of cells to hypoxia. HIFs have wide-ranging effects on metabolism, the tumor microenvironment (TME) and the extracellular matrix (ECM). Here we investigated the silencing effects of two of the three known isoforms,...

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Bibliographic Details
Main Authors: Eibhlin Goggins, Samata Kakkad, Yelena Mironchik, Desmond Jacob, Flonne Wildes, Balaji Krishnamachary, Zaver M. Bhujwalla
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558617304037

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http://www.sciencedirect.com/science/article/pii/S1476558617304037

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