Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures

Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures

Loss of canonical Notch signaling in vascular endothelial cells induces spontaneous formation of proto-typical tertiary lymphoid structures in mouse kidney, liver and lungs, which form around central arteries that acquire a high endothelial cell signature

Bibliographic Details
Main Authors: Susanne Fleig, Tamar Kapanadze, Jeremiah Bernier-Latmani, Julia K. Lill, Tania Wyss, Jaba Gamrekelashvili, Dustin Kijas, Bin Liu, Anne M. Hüsing, Esther Bovay, Adan Chari Jirmo, Stephan Halle, Melanie Ricke-Hoch, Ralf H. Adams, Daniel R. Engel, Sibylle von Vietinghoff, Reinhold Förster, Denise Hilfiker-Kleiner, Hermann Haller, Tatiana V. Petrova, Florian P. Limbourg
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29701-x

Internet

https://doi.org/10.1038/s41467-022-29701-x

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