A Nonclassical Mechanism of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus and Its Effect on Virulence

A Nonclassical Mechanism of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus and Its Effect on Virulence

ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is a group of pathogenic bacteria that are infamously resistant to β-lactam antibiotics, a property attributed to the mecA gene. Recent studies have reported that mutations associated with the promoter region of pbp4 demonstrated high level...

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Bibliographic Details
Main Authors: Nidhi Satishkumar, Li-Yin Lai, Nagaraja Mukkayyan, Bruce E. Vogel, Som S. Chatterjee
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
PBP4
Staphylococcus aureus
beta-lactam resistance
virulence
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02284-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02284-22

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