Direct access to pyrido/pyrrolo[2,1-b]quinazolin-9(1H)-ones through silver-mediated intramolecular alkyne hydroamination reactions

Direct access to pyrido/pyrrolo[2,1-b]quinazolin-9(1H)-ones through silver-mediated intramolecular alkyne hydroamination reactions

We report a synthetic methodology for the construction of the fused heterocyclic compounds pyrido[2,1-b]quinazolin-9(1H)-ones and pyrrolo[2,1-b]quinazolin-9(1H)-ones through an AgOTf-catalyzed intramolecular alkyne hydroamination reaction. The methodology is applicable to a wide scope of substrates...

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Bibliographic Details
Main Authors: Hengshuai Wang, Shengchao Jiao, Kerong Chen, Xu Zhang, Linxiang Zhao, Dan Liu, Yu Zhou, Hong Liu
Format: Article
Language:English
Published: Beilstein-Institut 2015-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
heterocyclic molecules
intramolecular alkyne hydroamination
silver
Online Access:https://doi.org/10.3762/bjoc.11.47

Internet

https://doi.org/10.3762/bjoc.11.47

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