NEK2 Promotes Cell Proliferation and Glycolysis by Regulating PKM2 Abundance via Phosphorylation in Diffuse Large B-Cell Lymphoma

NEK2 Promotes Cell Proliferation and Glycolysis by Regulating PKM2 Abundance via Phosphorylation in Diffuse Large B-Cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most frequent and commonly diagnosed subtype of NHL, which is characterized by high heterogeneity and malignancy, and most DLBCL patients are at advanced stages. The serine/threonine kinase NEK2 (NIMA-related kinase 2), a member of NIMA-related kinase (NE...

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Bibliographic Details
Main Authors: Lingna Zhou, Liya Ding, Yuqi Gong, Jing Zhao, Jing Zhang, Zhengrong Mao, Zhe Wang, Wei Zhang, Ren Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
diffuse large B-cell lymphoma
GSEA
glycolysis
NEK2
PKM2
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.677763/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.677763/full

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