Interferon Regulatory Factor 5 Mediates Lipopolysaccharide-Induced Neuroinflammation

Interferon Regulatory Factor 5 Mediates Lipopolysaccharide-Induced Neuroinflammation

BackgroundActivated microglia play a vital role in neuroinflammation in the central nervous system (CNS), which is associated with the pathogenesis and the progression of neurological diseases. Interferon regulatory factor 5 (IRF5) has been well established participating in inflammatory responses an...

Full description

Bibliographic Details
Main Authors: Ziqi Fan, Shuai Zhao, Yueli Zhu, Zheyu Li, Zhirong Liu, Yaping Yan, Jun Tian, Yanxing Chen, Baorong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
IRF5
siRNA interfering
intracerebroventricular
lipopolysaccharide
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.600479/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.600479/full

Similar Items