Case report: A successful second autologous hematopoietic stem cell transplantation in refractory systemic sclerosis, with positive effect on skin involvement, pulmonary function and microcirculation

Case report: A successful second autologous hematopoietic stem cell transplantation in refractory systemic sclerosis, with positive effect on skin involvement, pulmonary function and microcirculation

BackgroundSystemic sclerosis (SSc) is a complex autoimmune disease characterized by inflammation, vasculopathy and fibrosis of the skin and internal organs. Treatment with autologous hematopoietic cell transplantation (HCT) for progressive SSc has improved overall and event-free survival rates signi...

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Bibliographic Details
Main Authors: D.A. Haverkort, B.E. Kersten, A. van Rhenen, W.J.F.M. van der Velden, M.C. Vonk
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
systemic sclerosis
stem cell transplant (SCT)
nailfod capillaroscopy
Rodnan skin score
interstitial lung disease
microvascular abnormalities
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.925776/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.925776/full

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