Thymoquinone enhances cisplatin-induced neprotoxicity in high dose

Background: Cisplatin-induced nephrotoxicity is an important problem of the cancer treatments. The major bioactive component of Nigella sativa, thymoquinone (TQ) might limit the nephrotoxic effect of cisplatin in low doses. However, it is not clear how it can affect the kidney as an anti-cytotoxic a...

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Main Authors: Ahmet Dirican, Osman Sahin, Funda Tasli, Erkan Sogut, Yuksel Kucukzeybek, Ahmet Alacacioglu, Mustafa Gunes, Gulcan Saglam, Eyup Coban, Mustafa Oktay Tarhan, Buket Demirci
Format: Article
Language:English
Published: Turkiye Klinikleri 2016-01-01
Series:Journal of Oncological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452336415000060