Streptococcus suis Serotype 2 Infection Impairs Interleukin-12 Production and the MHC-II-Restricted Antigen Presentation Capacity of Dendritic Cells

Streptococcus suis Serotype 2 Infection Impairs Interleukin-12 Production and the MHC-II-Restricted Antigen Presentation Capacity of Dendritic Cells

Streptococcus suis is an important swine pathogen and emerging zoonotic agent. Encapsulated strains of S. suis modulate dendritic cell (DC) functions, leading to poorly activated CD4+ T cells. However, the antigen presentation ability of S. suis-stimulated DCs has not been investigated yet. In this...

Full description

Bibliographic Details
Main Authors: Corinne Letendre, Jean-Philippe Auger, Paul Lemire, Tristan Galbas, Marcelo Gottschalk, Jacques Thibodeau, Mariela Segura
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
Streptococcus suis
inflammation
dendritic cells
T cells
antigen presentation
MHC-II
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01199/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01199/full

Similar Items