Assessment of Cardiotoxicity after a Single Dose of Combretastatin A4-Phosphate in Dogs Using Two-Dimensional Speckle-Tracking Echocardiography

Assessment of Cardiotoxicity after a Single Dose of Combretastatin A4-Phosphate in Dogs Using Two-Dimensional Speckle-Tracking Echocardiography

Combretastatin A4-phosphate (CA4P) is a vascular disrupting agent that was recently described for the treatment of solid canine tumors. Conventional echocardiography and pulsed wave tissue Doppler imaging did not reveal cardiotoxicity in dogs, however, the gold standard for assessing myocardial dama...

Full description

Bibliographic Details
Main Authors: Gitte Mampaey, Arnaut Hellemans, Hilde de Rooster, Tom Schipper, Eline Abma, Bart J. G. Broeckx, Sylvie Daminet, Pascale Smets
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Animals
Subjects:
canine
systolic dysfunction
myocardial damage
heart failure
cardiac troponin I
global longitudinal strain
Online Access:https://www.mdpi.com/2076-2615/12/21/3005

Internet

https://www.mdpi.com/2076-2615/12/21/3005

Similar Items