Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures

Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures

Summary: Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this threat are urgently needed. Here, we have refined our previously established model of lethal H5N1 infection in cynomolgus macaques. An...

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Bibliographic Details
Main Authors: Masaru Kanekiyo, Rebecca A. Gillespie, Morgan Midgett, Katherine J. O’Malley, Connor Williams, Syed M. Moin, Megan Wallace, Luke Treaster, Kristine Cooper, Hubza Syeda, Gwenddolen Kettenburg, Hasala Rannulu, Tabitha Schmer, Lucia Ortiz, Priscila Da Silva Castanha, Jacqueline Corry, Mengying Xia, Emily Olsen, Daniel Perez, Gabin Yun, Barney S. Graham, Simon M. Barratt-Boyes, Douglas S. Reed
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Immunology
Virology
Model organism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223019077

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http://www.sciencedirect.com/science/article/pii/S2589004223019077

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