Chromatin structure predicts survival in glioma patients

Abstract The pathological changes in epigenetics and gene regulation that accompany the progression of low-grade to high-grade gliomas are under-studied. The authors use a large set of paired atac-seq and RNA-seq data from surgically resected glioma specimens to infer gene regulatory relationships i...

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Bibliographic Details
Main Authors: Matthew C. Garrett, Rebecca Albano, Troy Carnwath, Sanjit Shah, Daniel Woo, Michael Lamba, David R. Plas, Aditi Paranjpe, Krishna Roskin, Chuntao Zhao, Richard Lu
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11019-9