Dopamine agonist increases risk taking but blunts reward-related brain activity.

Dopamine agonist increases risk taking but blunts reward-related brain activity.

The use of D2/D3 dopaminergic agonists in Parkinson's disease (PD) may lead to pathological gambling. In a placebo-controlled double-blind study in healthy volunteers, we observed riskier choices in a lottery task after administration of the D3 receptor-preferring agonist pramipexole thus mimic...

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Bibliographic Details
Main Authors: Jordi Riba, Ulrike M Krämer, Marcus Heldmann, Sylvia Richter, Thomas F Münte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2423613?pdf=render

Internet

http://europepmc.org/articles/PMC2423613?pdf=render

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