Upregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective roles.

Transient Receptor Potential Ankyrin 1 (TRPA1) channels are localized on sensory nerves and several non-neural cells, but data on their functional significance are contradictory. We analysed the presence and alterations of TRPA1 in comparison with TRP Vanilloid 1 (TRPV1) at mRNA and protein levels i...

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Main Authors: József Kun, István Szitter, Agnes Kemény, Anikó Perkecz, László Kereskai, Krisztina Pohóczky, Aron Vincze, Szilárd Gódi, Imre Szabó, János Szolcsányi, Erika Pintér, Zsuzsanna Helyes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0108164