A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation

A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation

Nicotinamide adenine dinucleotide (NAD+) is an indispensable cofactor in all domains of life, and its homeostasis must be regulated tightly. Here we report that a Nudix-related transcriptional factor, designated MsNrtR (MSMEG_3198), controls the de novo pathway of NAD+biosynthesis in M. smegmatis, a...

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Bibliographic Details
Main Authors: Rongsui Gao, Wenhui Wei, Bachar H Hassan, Jun Li, Jiaoyu Deng, Youjun Feng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
acetylation
NrtR
NAD
mycobacterium
repression
Online Access:https://elifesciences.org/articles/51603

Internet

https://elifesciences.org/articles/51603

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