Detection of hemodynamic changes in a porcine lipopolysaccharide model of systemic inflammation using dynamic light scattering measurements of the microcirculation

Detection of hemodynamic changes in a porcine lipopolysaccharide model of systemic inflammation using dynamic light scattering measurements of the microcirculation

BackgroundThe microcirculation is affected during sepsis, yet there is currently no clinically available technology for sepsis detection in the microcirculation. This study aimed to detect microcirculatory changes using a dynamic light scattering (DLS) skin sensor during an endotoxic shock with a sy...

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Bibliographic Details
Main Authors: Louwrina H. te Nijenhuis, Norani H. Gangaram-Panday, Patricia A. C. Specht, Ilya Fine, Nimrod Elstein, Egbert G. Mik, Floor A. Harms, Irwin K. M. Reiss, Willem van Weteringen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Medicine
Subjects:
lipopolysaccharide (endotoxin)
microcirculation (skin)
dynamic light scattering (DLS)
animal model
sepsis-diagnostics
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1522630/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2025.1522630/full

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