CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice

CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice

Background: CD36, a member of the class B scavenger receptor family, participates in Toll-like receptor signaling on mononuclear phagocytes (MP) and can promote sterile pathogenic inflammation. We here analyzed the effect of CD36 deficiency on retinal inflammation and photoreceptor degeneration, the...

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Bibliographic Details
Main Authors: Sophie Lavalette, Jean-Baptiste Conart, Sara Touhami, Christophe Roubeix, Marianne Houssier, Sébastien Augustin, William Raoul, Christophe Combadière, Maria Febbraio, Huy Ong, Sylvain Chemtob, José-Alain Sahel, Cécile Delarasse, Xavier Guillonneau, Florian Sennlaub
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
age related macular degeneration
mononuclear phagocyte
CX3CR1
CD36
IL-6
photoreceptor
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03032/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.03032/full

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