Comparative assessment of hepatoprotective properties of Artesunate and flavonoids from Artemisia annua on acetaminophen and carbon tetrachloride-induced cytotoxicity in primary mice hepatocytes

Comparative assessment of hepatoprotective properties of Artesunate and flavonoids from Artemisia annua on acetaminophen and carbon tetrachloride-induced cytotoxicity in primary mice hepatocytes

Background: Artesunate (ART) is a semi-synthetized molecule from Artemisinin, an active compound isolated from the medicinal plant Artemisia annua, widely used for the treatment of malaria. Previous studies reported that ART may exert a dual effect on the liver. Accordingly, this study investigated...

Full description

Bibliographic Details
Main Authors: Marie Ange Djeungoue Petga, Arnaud Fondjo Kouam, Rosine Désirée Chougouo Kengne, Boris Rosnay Galani Tietcheu, Josué Simo Louokdom, Claude Bérenger Ngantchouko Ngalemo, Pascal Dieudonné Chuisseu Djamen, Paul Fewou Moundipa
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Metabolism Open
Subjects:
Artesunate
Flavonoid from Artemesia annua
Hepatotoxicity
Acetaminophen
Carbon tetrachloride
Antioxidant activities
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936823000130

Internet

http://www.sciencedirect.com/science/article/pii/S2589936823000130

Similar Items