An atlas of gross and histologic lesions and immunohistochemical immunoreactivity during the temporal progression of aerosolized Lassa virus induced hemorrhagic fever in cynomolgus macaques

An atlas of gross and histologic lesions and immunohistochemical immunoreactivity during the temporal progression of aerosolized Lassa virus induced hemorrhagic fever in cynomolgus macaques

Lassa virus (LASV) causes an acute multisystemic hemorrhagic fever in humans known as Lassa fever, which is endemic in several African countries. This manuscript focuses on the progression of disease in cynomolgus macaques challenged with aerosolized LASV and serially sampled for the development and...

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Bibliographic Details
Main Authors: Forrest Bohler, Kathleen Cashman, Eric Wilkinson, Joshua C. Johnson, Kyle Rosenke, Josh Shamblin, Lisa Hensley, Anna Honko, Carl Shaia
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Lassa virus
Lassa fever
cynomolgus macaques
non-human primate
histologic lesion
immunohistochemistry
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1341891/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1341891/full

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