A Three-Genes Signature Predicting Colorectal Cancer Relapse Reveals LEMD1 Promoting CRC Cells Migration by RhoA/ROCK1 Signaling Pathway

A Three-Genes Signature Predicting Colorectal Cancer Relapse Reveals LEMD1 Promoting CRC Cells Migration by RhoA/ROCK1 Signaling Pathway

ObjectiveColorectal cancer (CRC) patients that experience early relapse consistently exhibit poor survival. However, no effective approach has been developed for the diagnosis and prognosis prediction of postoperative relapsed CRC.MethodsMultiple datasets from the GEO database and TCGA database were...

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Bibliographic Details
Main Authors: Hui Zhang, Chenxin Xu, Feng Jiang, Jifeng Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
LEMD1
relapse model
RhoA
EMT
colorectal cancer
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.823696/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.823696/full

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