Mesenchymal Stem Cell Exosomes Enhance Posterolateral Spinal Fusion in a Rat Model

Spinal fusion, a common surgery performed for degenerative lumbar conditions, often uses recombinant human bone morphogenetic protein 2 (rhBMP-2) that is associated with adverse effects. Mesenchymal stromal/stem cells (MSCs) and their extracellular vesicles (EVs), particularly exosomes, have demonst...

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Bibliographic Details
Main Authors: Wing Moon Raymond Lam, Wen-Hai Zhuo, Long Yang, Rachel Tan, Sai Kiang Lim, Hwee Weng Dennis Hey, Wei Seong Toh
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/9/761