Triphenyl phosphate proved more potent than its metabolite diphenyl phosphate in inducing hepatic insulin resistance through endoplasmic reticulum stress

Triphenyl phosphate proved more potent than its metabolite diphenyl phosphate in inducing hepatic insulin resistance through endoplasmic reticulum stress

Triphenyl phosphate (TPHP) is a widely used flame retardant and plasticizer and has been detected extensively in environmental media, wildlife and human bodies. Several epidemiological and animal studies have revealed that TPHP exposure is positively associated with glucose homeostasis disruption an...

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Bibliographic Details
Main Authors: Junjie Yue, Xuan Sun, Xiaoyu Duan, Caiting Sun, Hao Chen, Hongwen Sun, Lianying Zhang
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Environment International
Subjects:
Triphenyl phosphate
Diphenyl phosphate
Transcriptional profiling
Insulin sensitivity
Endoplasmic reticulum stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412023000223

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http://www.sciencedirect.com/science/article/pii/S0160412023000223

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