Craig plot 2.0: an interactive navigation in the substituent bioisosteric space
Abstract Bioisosteric replacement is a standard technique that is used in medicinal chemistry to design analogs of bioactive molecules with similar biological activity and with additional improved characteristics. Successful application of this technique relies on a good knowledge of physicochemical...
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| Format: | Article |
| Language: | English |
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BMC
2020-01-01
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| Series: | Journal of Cheminformatics |
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| Online Access: | https://doi.org/10.1186/s13321-020-0412-1 |