The mitochondrial DNA mutations associated with cardiac arrhythmia investigated in an LQTS family

Objective(s): As mitochondrial oxidative stress is probably entailed in ATP production, a candidate modifier factor for the long QT syndrome (LQTS) could be mitochondrial DNA (mtDNA). It has been notified that ion channels' activities in cardiomyocytes are sensitive to the ATP level. Materials...

Full description

Bibliographic Details
Main Authors: Fatemeh Khatami, Mohammad Mehdi Heidari, Massoud Houshmand
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_3327_be6cba427a74e6d3e7b627cc114a7415.html