Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery.

<h4>Background</h4>Onchocerciasis (river blindness) caused by the filarial worm Onchocerca volvulus is a neglected tropical disease that affects the skin and eyes of humans. Mass drug administration with ivermectin (IVM) to control the disease often suffers from severe adverse events in...

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Bibliographic Details
Main Authors: Rene Bilingwe Ayiseh, Glory Enjong Mbah, Elvis Monya, Emmanuel Menang Ndi, Judy Sakanari, Sara Lustigman, Fidelis Cho-Ngwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011135