Daytime administration of melatonin has better protective effects on bone loss in ovariectomized rats
Abstract Objective To explore the difference in the protective effects of intraperitoneal injection of exogenous melatonin of daytime or nighttime on bone loss in ovariectomized (OVX) rats. Methods After bilateral ovariectomy and sham surgery, 40 rats were randomly divided into four groups: sham ope...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-023-03695-8 |