Daytime administration of melatonin has better protective effects on bone loss in ovariectomized rats

Abstract Objective To explore the difference in the protective effects of intraperitoneal injection of exogenous melatonin of daytime or nighttime on bone loss in ovariectomized (OVX) rats. Methods After bilateral ovariectomy and sham surgery, 40 rats were randomly divided into four groups: sham ope...

Full description

Bibliographic Details
Main Authors: Tian-lin Li, He-dong Liu, Mao-xian Ren, Zhi Zhou, Wen-kai Jiang, Min Yang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03695-8