METTL3 suppresses anlotinib sensitivity by regulating m6A modification of FGFR3 in oral squamous cell carcinoma

Abstract Background N6-methyladenosine (m6A) is an abundant nucleotide modification in mRNA, but there were few studies on its role in cancer drug sensitivity and resistance. Anlotinib has been proved to have effective antitumor effects in oral squamous cell carcinoma (OSCC) in our previous study. H...

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Bibliographic Details
Main Authors: Jie Chen, Shuai Li, Zhexun Huang, Congyuan Cao, Anxun Wang, Qianting He
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02715-7