An Aurora B-RPA signaling axis secures chromosome segregation fidelity

An Aurora B-RPA signaling axis secures chromosome segregation fidelity

Abstract Errors in chromosome segregation underlie genomic instability associated with cancers. Resolution of replication and recombination intermediates and protection of vulnerable single-stranded DNA (ssDNA) intermediates during mitotic progression requires the ssDNA binding protein Replication P...

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Bibliographic Details
Main Authors: Poonam Roshan, Sahiti Kuppa, Jenna R. Mattice, Vikas Kaushik, Rahul Chadda, Nilisha Pokhrel, Brunda R. Tumala, Aparna Biswas, Brian Bothner, Edwin Antony, Sofia Origanti
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38711-2

Internet

https://doi.org/10.1038/s41467-023-38711-2

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