Evolutionary shift from purifying selection towards divergent selection of SARS-CoV2 favors its invasion into multiple human organs
SARS-CoV2 virus is believed to be originated from a closely related bat Coronavirus RaTG13 lineage and uses its key entry-point residues in S1 protein to attach with human ACE2 receptor. SARS-CoV2 could enter human from bat with its poorly developed entry-point residues much before its known appeara...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Virus Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0168170222000405 |