Agitation predicts response of depression to botulinum toxin treatment in a randomized controlled trial

Agitation predicts response of depression to botulinum toxin treatment in a randomized controlled trial

In a randomized, controlled trial (n=30) we showed that botulinum toxin injection to the glabellar region produces a marked improvement in the symptoms of major depression. We hypothesized that the mood-lifting effect was mediated by facial feedback mechanisms. Here we assessed if agitation, which m...

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Bibliographic Details
Main Authors: Marc Axel Wollmer, Nadeem eKalak, Stephanie eJung, Claas eDeBoer, Michelle eMagid, Jason S Reichenberg, Serge eBrand, Edith eHolsboer-Trachsler, Tillmann H.C. Kruger
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Psychiatry
Subjects:
Psychomotor Agitation
personalized medicine
Major Depressive Disorder
randomized controlled trial
Type A Botulinum Toxins
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00036/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00036/full

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