SAMHD1 Is a Modulator of Nucleos(t)ide Analogues’ Efficacy

SAMHD1 Is a Modulator of Nucleos(t)ide Analogues’ Efficacy

Nucleos(t)ide analogues are commonly used in the treatment of infectious disease and cancer. SAMHD1 is a deoxyribonucleotide (dNTP) triphosphohydrolase which is involved in the regulation of the intracellular dNTP pool, whose function has been linked to viral restriction, cancer development, and aut...

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Bibliographic Details
Main Authors: Ifeanyi Ezeonwumelu, Marc Castellví, Eudald Felip, Maria Pujantell, Edurne Garcia-Vidal, Eva Riveira-Muñoz, Roger Badia, Bonaventura Clotet, Mireia Margelí, Ester Ballana
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
SAMHD1
dNTPs
nucleoside analogues
HIV
Online Access:https://www.mdpi.com/2504-3900/50/1/58

Internet

https://www.mdpi.com/2504-3900/50/1/58

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