Small bowel edema and lymphocytic duodenitis as severe reversible gastrointestinal toxicity of selpercatinib in RET fusion–positive non–small cell lung cancer: a case report

Small bowel edema and lymphocytic duodenitis as severe reversible gastrointestinal toxicity of selpercatinib in RET fusion–positive non–small cell lung cancer: a case report

IntroductionRearranged during transfection (RET) gene rearrangements occur in 1%–2% of non–small cell lung cancer (NSCLC). Because of the results of the study LIBRETTO-001, selpercatinib has been approved as the first-line treatment for patients with RET fusion–positive advanced NSCLC. Selpercatinib...

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Bibliographic Details
Main Authors: Daniela Scattolin, Elena Scagliori, Antonio Scapinello, Alberto Fantin, Valentina Guarneri, Giulia Pasello
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
NSCLC
RET
selpercatinib
gastrointestinal toxicity
small bowel
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1201599/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1201599/full

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