Pilot Study Showing Feasibility of Phosphoproteomic Profiling of Pathway-Level Molecular Alterations in Barrett’s Esophagus

Pilot Study Showing Feasibility of Phosphoproteomic Profiling of Pathway-Level Molecular Alterations in Barrett’s Esophagus

(1) Background: Barrett’s esophagus is a major risk factor for esophageal adenocarcinoma. In this pilot study, we employed precision mass spectrometry to map global (phospho)protein perturbations in Barrett’s esophagus lesions and adjacent normal tissue to glean insights into disease progression. (2...

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Bibliographic Details
Main Authors: Jarrod Moore, Ryan Hekman, Benjamin C. Blum, Matthew Lawton, Sylvain Lehoux, Matthew Stachler, Douglas Pleskow, Mandeep S. Sawhney, Richard D. Cummings, Andrew Emili, Alia Qureshi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
pre-cancerous lesion
biopsy
systems biology
mass spectrometry
disease signature
Online Access:https://www.mdpi.com/2073-4425/13/7/1215

Internet

https://www.mdpi.com/2073-4425/13/7/1215

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