Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat

Abstract Background Spinal cord injury (SCI) in young adults leads to severe sensorimotor disabilities as well as slowing of growth. Systemic pro‐inflammatory cytokines are associated with growth failure and muscle wasting. Here we investigated whether intravenous (IV) delivery of small extracellula...

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Bibliographic Details
Main Authors: Masahito Nakazaki, Karen L. Lankford, Hideaki Yamamoto, Yoshiyuki Mae, Jeffery D. Kocsis
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1284