Hypermethylation and loss of retinoic acid receptor responder 1 expression in human choriocarcinoma

Hypermethylation and loss of retinoic acid receptor responder 1 expression in human choriocarcinoma

Abstract Background Human placental development resembles tumorigenesis, due to the invasive and fusogenic potential of trophoblasts. However, these features are tightly controlled in trophoblasts. Disturbance of this spatial and temporal regulation is thought to contribute to the rare formation of...

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Bibliographic Details
Main Authors: H. Huebner, R. Strick, D. L. Wachter, S. Kehl, P. L. Strissel, R. Schneider-Stock, A. Hartner, W. Rascher, L. C. Horn, M. W. Beckmann, M. Ruebner, F. B. Fahlbusch
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Placenta
RARRES1
Retinoic acid
Choriocarcinoma
DNA methylation
TIG1
Online Access:http://link.springer.com/article/10.1186/s13046-017-0634-x

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http://link.springer.com/article/10.1186/s13046-017-0634-x

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