The coherence between PSMC6 and α-ring in the 26S proteasome is associated with Alzheimer’s disease

The coherence between PSMC6 and α-ring in the 26S proteasome is associated with Alzheimer’s disease

Alzheimer’s disease (AD) is a heterogeneous age-dependent neurodegenerative disorder. Its hallmarks involve abnormal proteostasis, which triggers proteotoxicity and induces neuronal dysfunction. The 26S proteasome is an ATP-dependent proteolytic nanomachine of the ubiquitin-proteasome system (UPS) a...

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Bibliographic Details
Main Authors: Jing Xiong, Xinping Pang, Xianghu Song, Lin Yang, Chaoyang Pang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer’s disease
proteasome
support vector machine
entropy
determinant
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1330853/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1330853/full

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