Inhibition of NLRP3 by Fermented Quercetin Decreases Resistin-Induced Chemoresistance to 5-Fluorouracil in Human Colorectal Cancer Cells

Inhibition of NLRP3 by Fermented Quercetin Decreases Resistin-Induced Chemoresistance to 5-Fluorouracil in Human Colorectal Cancer Cells

The drug resistance of colorectal cancer (CRC) cells against 5-fluorouracil (5-FU) therapy is a major challenge to successful cancer treatment. While previous studies have proposed several 5-FU resistance mechanisms, the effects of the adipokines on cancer cells remain unclear. Thus, this study inve...

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Bibliographic Details
Main Authors: Ko-Chao Lee, Kuen-Lin Wu, Chia-Kung Yen, Shun-Fu Chang, Cheng-Nan Chen, Ying-Chen Lu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceuticals
Subjects:
colorectal cancer
resistin
NLRP3
quercetin
<i>Lactobacillus plantarum</i>
drug resistance
Online Access:https://www.mdpi.com/1424-8247/15/7/798

Internet

https://www.mdpi.com/1424-8247/15/7/798

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